Description
Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer (1,2). It is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.
Protein Sequence:
ARTKQ TARKS TGGKA PRKQL ATKAA RKSAP STGGV
KKPHR YRPGT VALRE IRRYQ KSTEL LIRKL PFQRL VREIA QDFKT DLRFQ SAAIG ALQEA SEAYL
VGLFE DTNLC AIHAK RVTIM PKDIQ LARRI RGERA (Genbank accession number: P84243)
Product Source
An E. coli strain that carries a plasmid encoding the cloned human histone H3.3 gene, H3F3A or H3F3B. (Genbank accession number: AK311905)
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