Catalog # M2508 was discontinued on December 18, 2023 Product Introduction Histone H2A combines with Histone H2B to form the H2A/H2B heterodimer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. Histones are modified by various enzymes and can act as substrates for them. These modifications have been shown to be important in gene regulation. Because the histones are folded with their subunit partners, the dimer may be a better substrate for specific enzymes and modifications. Highly pure, recombinant protein Mass confirmed by ESI-TOF MS Tested for exonuclease, endonuclease and protease contamination Bioz Badge Exists : True